Guide to Route 4721: from Lisbon Oriente to Setúbal, with shopping, science, and outings along the way

Guide to Route 4721: from Lisbon Oriente to Setúbal, with shopping, science, and outings along the way

With few departures on weekdays, route 4721 connects Gare do Oriente in Lisbon to the Setúbal terminal and can be used as a starting point for exploring attractions in Parque das Nações and different shopping, cultural, and leisure experiences in Setúbal.

In the capital, the route begins in one of Lisbon’s most modern and best-connected areas: Parque das Nações. The region combines contemporary architecture, riverside walks along the Tagus, shopping centers, restaurants, and family attractions, creating a setting quite different from Lisbon’s historic center.

After the connection to Setúbal, the route brings passengers closer to an area marked by Praça de Touros Carlos Relvas, Avenida Dom João II, and the ITS terminal. From these points, it is possible to continue on foot or use other urban transportation options to reach the city center, green spaces, traditional shops, and the city’s riverside area.

The distances indicated below are approximate estimates based on the coordinates provided and the position of the stops, and may vary depending on the route chosen, crossings, and available access points. According to the information provided, the route operates only on weekdays: there are 2 departures in the Lisbon–Setúbal direction and 3 departures in the Setúbal–Lisbon direction. There are no departures on Saturdays, Sundays, or public holidays. The fare and operator were not provided.

Centro Vasco da Gama

Practically next to Gare do Oriente, Centro Vasco da Gama is the most convenient option for anyone getting off at the first stop of route 4721 and looking for shops, restaurants, and services without having to move away from the terminal. The shopping center is integrated into Parque das Nações’ main transportation hub, with access by bus, metro, train, and car.

It is a good choice for a break before the trip, a quick meal, or taking care of everyday shopping. The offerings include a variety of retail outlets, dining, and leisure areas, while the location makes it possible to combine the visit with a walk through the architecture and public spaces of Parque das Nações.

• 📍 Location: Parque das Nações, next to Gare do Oriente, Lisbon.
• 🚏 Nearest stop/section of the route and approximate distance: Gare do Oriente 21-C, approximately 0.2 km away.
• 🏷️ Category: Shopping center, retail, and dining.
• ⭐ Distinguishing feature: It is the most accessible point on the itinerary, with direct connections to several modes of transport and a wide variety of shops and restaurants.

Lisbon Oceanarium

A few minutes’ walk from Gare do Oriente, the Lisbon Oceanarium is one of Parque das Nações’ best-known attractions. The visit is organized around a large central aquarium and different marine habitats, with species such as sharks, sea otters, rays, ocean sunfish, sea dragons, and penguins.

The space combines entertainment and environmental education in an experience especially interesting for families, first-time visitors, and anyone who wants an outing protected from the sun or rain. The permanent exhibition One Planet, One Ocean is complemented by temporary exhibitions, whose program may change throughout the year.

• 📍 Location: Esplanada Dom Carlos I, Parque das Nações, Lisbon.
• 🚏 Nearest stop/section of the route and approximate distance: Gare do Oriente 21-C, approximately 0.9 km away.
• 🏷️ Category: Tourist attraction, aquarium, and family leisure.
• ⭐ Distinguishing feature: The large central aquarium and the focus on ocean conservation make the visit a visual and educational experience.

Knowledge Pavilion

For those who prefer an interactive attraction, the Knowledge Pavilion – Ciência Viva Center offers exhibitions in which visitors are invited to touch, test, observe, and experiment. The museum is located at Largo José Mariano Gago, in the Parque das Nações area, and is an option that works well for both children and curious adults.

The program includes permanent and temporary exhibitions, family activities, and experiences related to science, technology, nature, and behavior. In 2026, the exhibition Super Animals! Incredible by Nature presents interactive modules about the extraordinary abilities of animals living in Portugal, and is expected to remain on display until September.

• 📍 Location: Largo José Mariano Gago, Parque das Nações, Lisbon.
• 🚏 Nearest stop/section of the route and approximate distance: Gare do Oriente 21-C, approximately 0.8 km away.
• 🏷️ Category: Science museum, exhibitions, and family entertainment.
• ⭐ Distinguishing feature: The practical, interactive concept makes the visit more participatory than a conventional exhibition.

Alegro Setúbal

At the destination, Alegro Setúbal brings shopping, services, dining, and entertainment together in a single complex. The center is located on Avenida Antero de Quental and offers fashion, beauty, technology, and wellness stores, as well as an Auchan hypermarket, Cinema City, a gym, pharmacy, and other services.

It is an especially useful stop for anyone arriving in Setúbal without a defined itinerary or needing to combine a meal with a movie and some shopping. The space also maintains family initiatives and accessibility measures, such as Quiet Hour on Sundays, when the environment is adapted to reduce sound and light stimuli.

• 📍 Location: Avenida Antero de Quental, No. 2, Setúbal.
• 🚏 Nearest stop/section of the route and approximate distance: Setúbal (ITS) Interior P1, approximately 0.7 to 1 km away.
• 🏷️ Category: Shopping center, hypermarket, cinema, dining, and services.
• ⭐ Distinguishing feature: It brings retail, food, cinema, and services together in one place, with views of the Arrábida Mountains and the Sado River.

Bonfim Garden

Bonfim Garden is the main invitation to take a green break in the center of Setúbal. Dating back to the 16th century and covering more than 42,000 square meters, the park combines wooded areas, a lake, a children’s playground, dining, and spaces for rest and outdoor activities.

The garden also contains elements that help tell the story of and express the local identity, such as the Pasmadinhos of Setúbal, a sundial, and the city’s stone coat of arms. It is a suitable option for an unhurried walk, resting after the trip, or taking a more peaceful outing before continuing to the downtown area.

• 📍 Location: Bonfim Garden, Setúbal.
• 🚏 Nearest stop/section of the route and approximate distance: Avenida Dom João II, next to Praça de Touros, approximately 1.3 to 1.8 km away.
• 🏷️ Category: Urban park and leisure.
• ⭐ Distinguishing feature: It is one of the city’s historic green spaces and combines nature, leisure facilities, and cultural references.

Livramento Market

Livramento Market is one of the most interesting stops for anyone who wants to experience Setúbal through its fresh produce, fishing, and regional gastronomy. Located on Avenida Luísa Todi, the market is known for its tile-covered architecture and its variety of stalls selling fish, seafood, fruit, vegetables, meat, cheese, flowers, aromatic herbs, and grocery products.

More than a shopping space, Livramento serves as a meeting point for residents, merchants, and visitors. The best strategy is to arrive in the morning, when activity is busiest and the selection of products is at its peak. According to the municipal tourism information consulted, the market is open from Tuesday to Sunday, during the morning and early afternoon.

• 📍 Location: Avenida Luísa Todi, No. 163, Setúbal.
• 🚏 Nearest stop/section of the route and approximate distance: Setúbal (ITS) Interior P1, approximately 1.8 to 2.3 km away.
• 🏷️ Category: Traditional market, shopping, and gastronomy.
• ⭐ Distinguishing feature: The combination of tiles, fresh food retail, and a popular atmosphere makes the market one of the city’s most authentic experiences.

Casa da Baía

On Avenida Luísa Todi, Casa da Baía serves as a gateway to the Setúbal region. Housed in a building from the first half of the 18th century, classified as Municipal Heritage, the facility includes a tourist information office, a regional products shop, a wine shop, a café, exhibitions, and event spaces.

The location is particularly useful for anyone wishing to plan other outings around the city, the Arrábida Mountains, the beaches, and the Sado region. Casa da Baía also houses CIRES, the Sado Estuary Bottlenose Dolphin Interpretation Center, dedicated to the population of dolphins that lives in the bay.

• 📍 Location: Avenida Luísa Todi, No. 468, Setúbal.
• 🚏 Nearest stop/section of the route and approximate distance: Setúbal (ITS) Interior P1, approximately 2 to 2.5 km away.
• 🏷️ Category: Tourism, regional products, exhibitions, café, and events.
• ⭐ Distinguishing feature: It brings together tourist information and local flavors, including wines, cheeses, and sweets from the Setúbal Peninsula.

Banco de Portugal Municipal Gallery

To include art and heritage in the itinerary, the Banco de Portugal Municipal Gallery is located on Avenida Luísa Todi itself, near Livramento Market. The space occupies a former bank building with Art Nouveau characteristics, designed by architect Arnaldo Adães Bermudes.

Since 2013, the property has operated as a municipal gallery and hosted exhibitions and cultural events connected to the Setúbal Museum and the Convent of Jesus. The visit can be combined with the market and a walk along the avenue, creating a small cultural circuit in the city center.

• 📍 Location: Avenida Luísa Todi, No. 19, Setúbal.
• 🚏 Nearest stop/section of the route and approximate distance: Setúbal (ITS) Interior P1, approximately 2 to 2.5 km away.
• 🏷️ Category: Art gallery, heritage, and exhibitions.
• ⭐ Distinguishing feature: It combines contemporary exhibitions with a historic building featuring distinctive architecture along the cultural axis of Avenida Luísa Todi.

Route 4721 serves a highly specific journey, with only a few departures on weekdays, but offers two strategically located arrival points. In Lisbon, getting off at Gare do Oriente places passengers at the heart of Parque das Nações, near a shopping center, aquarium, and science museum. In Setúbal, getting off at ITS allows passengers to choose between the convenience of Alegro and continuing on to the parks, markets, cultural spaces, and tourist facilities in the city center. Since there is no service on weekends or public holidays, it is important to check the desired departure time in advance and plan the walk or any connecting transport.

Sources

• Centro Vasco da Gama — visits, access, and services
• Lisbon Oceanarium — exhibitions
• Knowledge Pavilion — exhibitions and visitor information
• Alegro Setúbal — shops, dining, and leisure
• VisitSetubal — urban parks in Setúbal
• VisitSetubal — Livramento Market
• VisitSetubal — Casa da Baía
• VisitSetubal — Banco de Portugal Municipal Gallery